Phospholipase D Family Member 4, a Transmembrane Glycoprotein with No Phospholipase D Activity, Expression in Spleen and Early Postnatal Microglia
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چکیده
منابع مشابه
Phospholipase D Family Member 4, a Transmembrane Glycoprotein with No Phospholipase D Activity, Expression in Spleen and Early Postnatal Microglia
BACKGROUND Phospholipase D (PLD) catalyzes conversion of phosphatidylcholine into choline and phosphatidic acid, leading to a variety of intracellular signal transduction events. Two classical PLDs, PLD1 and PLD2, contain phosphatidylinositide-binding PX and PH domains and two conserved His-x-Lys-(x)(4)-Asp (HKD) motifs, which are critical for PLD activity. PLD4 officially belongs to the PLD fa...
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The expression level of phospholipase D (PLD) was examined in the lungs of mice during postnatal development. Immunoprecipitation analysis revealed a moderate basal level of PLD1 in the lungs at postnatal 1 week, with a gradual increase occurring until week 4. The pattern of PLD2 paralleled that of PLD1, although the quantity of PLD2 was markedly less. PLD was immunostained in the most bronchio...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0013932